Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568211 | 0.86 | AOX1 (0.53) | AOX1HDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL7570655 | 0.85 | AOX1 (0.45) | AOX1HDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL7565049 | 0.85 | AOX1 (0.45) | AOX1HDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL8624362 | 0.80 | TERT (0.41) | AOX1HDAC1HDAC6PARP1TAS1R3 | |
| SCHEMBL8412028 | 0.78 | AOX1 (0.39) | AOX1HDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL7570661 | 0.78 | AOX1 (0.57) | AOX1HDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL7567407 | 0.77 | CTSS (0.46) | AOX1HDAC1HDAC6GAAPOLB | |
| SCHEMBL7564042 | 0.77 | AOX1 (0.46) | AOX1HDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL7027447 | 0.76 | AOX1 (0.78) | AOX1HDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL8415172 | 0.76 | AOX1 (0.38) | AOX1HDAC1HDAC6ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |