Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A known ✓ | P20648 | 1/20 | 0.31 |
| ▸ | ATP4B known ✓ | P51164 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 2/20 | 0.59 |
| ▸ | CCR8 | P51685 | 2/20 | 0.59 |
| ▸ | CCR5 | P51681 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL1714698 | 0.96 | CCR1 (0.59) | CCR1CCR8CCR5NPC1HSP90AA1 | |
| SCHEMBL1714606 | 0.96 | CCR1 (0.59) | CCR1CCR8CCR5NPC1HSP90AA1 | |
| SCHEMBL1714162 | 0.96 | CCR1 (0.59) | CCR1CCR8CCR5NPC1HSP90AA1 | |
| SCHEMBL862479 | 0.80 | CCR1 (0.68) | CCR1CCR8CCR5NPC1HSP90AA1 | |
| SCHEMBL16132489 | 0.76 | CCR1 (0.61) | CCR1CCR8CCR5NPC1HSP90AA1 | |
| SCHEMBL1715320 | 0.76 | CCR1 (0.61) | CCR1CCR8CCR5NPC1HSP90AA1 | |
| SCHEMBL136654 | 0.75 | CCR1 (1.00) | CCR1CCR8CCR5NPC1HSP90AA1 | |
| SCHEMBL28297883 | 0.75 | CCR1 (1.00) | CCR1CCR8CCR5NPC1HSP90AA1 | |
| SCHEMBL4303286 | 0.74 | CCR1 (0.59) | CCR1CCR8CCR5L3MBTL1CYP1A2 | |
| SCHEMBL2431810 | 0.74 | CCR1 (0.59) | CCR1CCR8CCR5NPC1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486549-B1 | ORGANIC ELECTROLUMINESCENT ELEMENT | TOYOTA JIDOSHOKKI KK (JP) | 2012-01-11 | — | — | EP | disclosed |
| EP-1755362-B1 | ORGANIC EL DEVICE | TOYOTA JIDOSHOKKI KK (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-7854998-B2 | Organic EL devices | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2010-12-21 | — | — | US | disclosed |
| EP-1489154-B1 | ORGANIC ELECTROLUMINESCENCE DEVICE | TOYOTA JIDOSHOKKI KK (JP) | 2009-05-13 | — | — | EP | disclosed |
| US-7521567-B2 | Amine compound and uses thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-21 | — | — | US | disclosed |
| US-20080290788-A1 | Organic el Devices | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2008-11-27 | — | — | US | disclosed |
| US-7419727-B2 | Organic electroluminescent device | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2008-09-02 | — | — | US | disclosed |
| US-7338720-B2 | Organic electroluminescent element | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2008-03-04 | — | — | US | disclosed |
| US-7252892-B2 | Organic electroluminescence device | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2007-08-07 | — | — | US | disclosed |
| EP-1755362-A1 | ORGANIC EL DEVICE | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2007-02-21 | — | — | EP | disclosed |
| US-20070018568-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2007-01-25 | — | — | US | disclosed |
| US-20060228577-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2006-10-12 | — | — | US | disclosed |
| US-20060226421-A1 | Amine compound and uses thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KENKYUJO (JP) | 2006-10-12 | — | — | US | disclosed |
| US-20060192473-A1 | Organic electroluminescent device | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1599074-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-11-23 | — | — | EP | disclosed |
| EP-1560469-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-20050089713-A1 | Organic electroluminescent element | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2005-04-28 | — | — | US | disclosed |
| US-20050084707-A1 | Organic electroluminescence device | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2005-04-21 | — | — | US | disclosed |
| EP-1489154-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2004-12-22 | — | — | EP | disclosed |
| EP-1486549-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2004-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060226421-A1 | Amine compound and uses thereof | PNMT, TYR, PAM | ATP4A 4514/4885ATP4B 3201/4885CCR1 4017/4885 |
| US-20050084707-A1 | Organic electroluminescence device | ELAVL1, SELE, CELF2 | ATP4A 3773/4885ATP4B 3544/4885CCR1 4055/4885 |
| US-20050089713-A1 | Organic electroluminescent element | SOD3, CELF2, SOD1 | ATP4A 2571/4885ATP4B 2385/4885CCR1 4096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.