Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8742982 | 0.84 | KMT2A (0.52) | RAB9AKMT2APKMNPC1MEN1 | |
| SCHEMBL254774 | 0.82 | CES1 (0.70) | RAB9AKMT2ANPC1MEN1CES1 | |
| SCHEMBL254773 | 0.82 | CES1 (0.65) | KMT2APKMMEN1CES1CES2 | |
| SCHEMBL10373812 | 0.81 | GAA (0.62) | RAB9ACES1CES2TSHRALDH1A1 | |
| Methane SCHEMBL28800504 | 0.81 | CES1 (0.68) | RAB9AKMT2ANPC1MEN1CES1 | |
| SCHEMBL10743516 | 0.81 | MAPT (0.60) | RAB9AKMT2ANPC1MEN1TSHR | |
| Methylamine SCHEMBL29169653 | 0.81 | TSHR (0.60) | KMT2APKMMEN1CES1CES2 | |
| SCHEMBL4256409 | 0.81 | RAB9A (0.64) | RAB9AKMT2APKMNPC1MEN1 | |
| SCHEMBL30258384 | 0.81 | RAB9A (0.64) | RAB9AKMT2APKMNPC1MEN1 | |
| SCHEMBL6355275 | 0.80 | ALDH1A1 (0.53) | RAB9AKMT2ANPC1MEN1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841924-A1 | BENZIMIDAZOLE COMPOUNDS | NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997004771-A1 | BENZIMIDAZOLE COMPOUNDS | NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) | 1997-02-13 | — | — | WO | disclosed |