Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGAM1 | P18669 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625881 | 0.94 | BRD4 (0.45) | BRD4ALDH1A1HRH4CYP1A2CNR1 | |
| SCHEMBL8624540 | 0.91 | PGAM1 (0.40) | PGAM1BRD4PARP14CNR1CNR2 | |
| SCHEMBL8628563 | 0.91 | BRD4 (0.42) | PGAM1BRD4PARP14AURKAKDR | |
| SCHEMBL8625789 | 0.91 | BRD4 (0.43) | BRD4ALDH1A1HRH4CYP1A2CNR1 | |
| SCHEMBL8624680 | 0.85 | GAA (0.45) | ALDH1A1 | |
| SCHEMBL8624605 | 0.85 | BRD4 (0.47) | BRD4ALDH1A1PARP14AURKAKDR | |
| SCHEMBL8624802 | 0.85 | KDM2B (0.39) | BRD4CNR1CNR2 | |
| SCHEMBL8624803 | 0.84 | ALDH1A1 (0.44) | BRD4ALDH1A1HRH4CYP1A2CNR1 | |
| SCHEMBL8630282 | 0.82 | PGAM1 (0.39) | PGAM1BRD4PARP14AURKAKDR | |
| SCHEMBL8628033 | 0.81 | ALDH1A1 (0.42) | BRD4ALDH1A1HRH4CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849912-A | Biphenyl derivatives | EISAI CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |