Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.42 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624605 | 0.94 | BRD4 (0.47) | BRD4PARP14CSF1RFLT3RAD52 | |
| SCHEMBL8630282 | 0.91 | PGAM1 (0.39) | BRD4PGAM1PARP14AURKAKDR | |
| SCHEMBL8625656 | 0.91 | PGAM1 (0.41) | BRD4PGAM1PARP14FLT3AURKA | |
| SCHEMBL8624822 | 0.91 | BRD4 (0.44) | BRD4CSF1RRAD52TACR1DRD2 | |
| SCHEMBL8627347 | 0.85 | MITF (0.39) | BRD4PARP14RAD52 | |
| SCHEMBL8625881 | 0.85 | BRD4 (0.45) | BRD4FLT3AURKAKDR | |
| SCHEMBL8628439 | 0.85 | CCNA2 (0.37) | BRD4RAD52DRD2 | |
| Hydrochloric Acid SCHEMBL8625633 | 0.84 | BRD4 (0.38) | BRD4PARP14RAD52 | |
| SCHEMBL8624540 | 0.82 | PGAM1 (0.40) | BRD4PGAM1PARP14 | |
| SCHEMBL8629280 | 0.82 | MITF (0.41) | BRD4RAD52DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849912-A | Biphenyl derivatives | EISAI CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |