Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14596620 | 0.84 | KMT2A (0.51) | SMN1; SMN2RAB9AMAPTNPC1PTPN1 | |
| SCHEMBL13660333 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2RAB9AMAPTNPC1POLB | |
| SCHEMBL11812611 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTMAPK1LMNAPOLB | |
| SCHEMBL444635 | 0.77 | PRMT1 (0.41) | BCAT2ADORA3SMN1; SMN2RAB9AMAPT | |
| Dimethylamine SCHEMBL9400427 | 0.74 | MEN1 (0.39) | BCAT2ADORA3SMN1; SMN2RAB9AMAPT | |
| Diethylamine SCHEMBL7761030 | 0.71 | MEN1 (0.36) | BCAT2SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL6931199 | 0.69 | KMT2A (0.52) | SMN1; SMN2RAB9AMAPTNPC1PTPN1 | |
| SCHEMBL124737 | 0.69 | MEN1 (0.72) | BCAT2SMN1; SMN2MAPTLMNAPOLB | |
| SCHEMBL14596448 | 0.65 | GAA (0.37) | SMN1; SMN2MAPTLMNAPOLBGAA | |
| SCHEMBL24202631 | 0.63 | SIRT1 (0.83) | SMN1; SMN2RAB9AMAPTNPC1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10045588-A | — | — | None | — | — | JP | disclosed |
| JP-10218771-A | — | — | None | — | — | JP | disclosed |
| JP-H10218771-A | PLATELET-ORIGINATING VASCULAR ENDOTHELIAL CELL GROWTH FACTOR INHIBITOR CONTAINING PYRAZOLONE COMPOUND OR ITS SALT | ISHIHARA SANGYO KAISHA LTD | 1998-08-18 | — | — | JP | disclosed |
| JP-H1045588-A | ALPHA-GLUCOSIDASE INHIBITOR CONTAINING PYRAZOLONE-BASED COMPOUND OR ITS SALT | ISHIHARA SANGYO KAISHA LTD | 1998-02-17 | — | — | JP | disclosed |