SCHEMBL13660333

SCHEMBL13660333

CC(C)C(=O)NC1=NN(c2ccccc2)C(=O)C1(Br)Br

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
RAB9A P51151 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 3/20 0.44
KDM4E B2RXH2 1/20 0.44
CASP3 P42574 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPT P10636 2/20 0.42
RXFP1 Q9HBX9 1/20 0.42
NPSR1 Q6W5P4 2/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
POLB P06746 2/20 0.39
ADORA1 P30542 2/20 0.38
GAA P10253 3/20 0.38
ADORA2A P29274 1/20 0.37
MDM4 O15151 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14596620 0.85 KMT2A (0.51) ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E
SCHEMBL8625305 0.81 BCAT2 (0.44) RAB9ASMN1; SMN2NPC1KDM4EMEN1
SCHEMBL11812611 0.76 SMN1; SMN2 (0.39) ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL14596448 0.74 GAA (0.37) ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL6931199 0.70 KMT2A (0.52) ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E
SCHEMBL10339505 0.67 SMN1; SMN2 (0.42) ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL9886 0.66 ALDH1A1 (0.85) ALDH1A1RAB9ASMN1; SMN2NPC1MEN1
SCHEMBL19425986 0.66 ALDH1A1 (0.85) ALDH1A1RAB9ASMN1; SMN2NPC1MEN1
Hydrochloric Acid SCHEMBL9145715 0.64 ALDH1A1 (0.81) ALDH1A1RAB9ASMN1; SMN2NPC1MEN1
SCHEMBL11659850 0.64 ALDH1A1 (0.81) ALDH1A1RAB9ASMN1; SMN2NPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090263744-A1 ETHYLENICALLY UNSATURATED COMPOUND, LIGHT SENSITIVE COMPOSITION, LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND PRINTING PROCESS EMPLOYING THE SAME KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-10-22 US disclosed
US-20090075201-A1 PLANOGRAPHIC PRINTING PLATE MATERIAL, AND CYCLIC UREIDE MOIETY-CONTAINING PHENOLIC RESIN AND ITS SYNTHETIC PROCESS KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-03-19 US disclosed
US-20090075201-A1 PLANOGRAPHIC PRINTING PLATE MATERIAL, AND CYCLIC UREIDE MOIETY-CONTAINING PHENOLIC RESIN AND ITS SYNTHETIC PROCESS KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-03-19 US disclosed
US-20090042134-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2009-02-12 US disclosed
US-20090042134-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2009-02-12 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
US-20080166662-A1 Plate-Making Method of Planographic Printing Plate and Imagewise Exposure Device KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-10 US disclosed
US-20080160445-A1 Planographic printing plate material, and method of preparing planographic printing plate employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-03 US disclosed
US-20080131812-A1 Resin for printing plate material and lithographic printing plate material by use thereof KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-06-05 US disclosed
US-20080131812-A1 Resin for printing plate material and lithographic printing plate material by use thereof KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-06-05 US disclosed
US-20080113295-A1 LIGHT SENSITIVE PRINTING PLATE MATERIAL, PRINTING PLATE AND PROCESS OF PREPARING THE SAME KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-05-15 US disclosed
US-20070281246-A1 Processing method of light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-12-06 US disclosed
US-20070281246-A1 Processing method of light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-12-06 US disclosed
EP-1859955-A1 LITHOGRAPHIC PRINTING PLATE MAKING METHOD AND IMAGE EXPOSING SYSTEM Konica Minolta Medical & Graphic, Inc. (JP) 2007-11-28 EP disclosed
US-7273692-B2 Planographic printing plate material and planographic printing plate preparing process KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-09-25 US disclosed
US-7252926-B2 Planographic printing plate material and preparing process of planographic printing plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-08-07 US disclosed
US-7252926-B2 Planographic printing plate material and preparing process of planographic printing plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-08-07 US disclosed
US-7192691-B2 Method of manufacturing light sensitive planographic printing plates and method of using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-03-20 US disclosed
US-7172851-B2 Light sensitive composition, planographic printing plate material, and image formation method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-02-06 US disclosed
US-7169535-B2 Photosensitive composition and photosensitive lithographic printing plate KONICA MINOLTA HOLDINGS, INC. (JP) 2007-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090263744-A1 ETHYLENICALLY UNSATURATED COMPOUND, LIGHT SENSITIVE COMPOSITION, LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND PRINTING PROCESS EMPLOYING THE SAME ELOVL1, ELOVL6, ELOVL3 ALDH1A1 1057/4885RAB9A 4163/4885SMN1; SMN2 4662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.