Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.40 |
| ▸ | CA9 | Q16790 | 12/20 | 0.40 |
| ▸ | CA12 | O43570 | 11/20 | 0.40 |
| ▸ | CA1 | P00915 | 8/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820618 | 0.79 | MAPT (0.54) | L3MBTL1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL13401049 | 0.78 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL14557033 | 0.76 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8628373 | 0.74 | CA2 (0.51) | CA2CA9CA12CA1CA7 | |
| SCHEMBL8629241 | 0.73 | CA2 (0.40) | CA2CA9CA12CA1CA7 | |
| SCHEMBL4212359 | 0.70 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL19604862 | 0.69 | LMNA (0.53) | L3MBTL1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL28820683 | 0.69 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTTHRBHPGD | |
| SCHEMBL4208984 | 0.69 | TSHR (0.59) | L3MBTL1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL4203351 | 0.69 | TSHR (0.42) | L3MBTL1ALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |