Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 6/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624803 | 0.88 | ALDH1A1 (0.44) | ALDH1A1TDP2NSD2PLA2G1BATG4B | |
| SCHEMBL8625789 | 0.86 | BRD4 (0.43) | ALDH1A1TDP2NSD2PLA2G1BATG4B | |
| SCHEMBL8625881 | 0.83 | BRD4 (0.45) | ALDH1A1TDP2NSD2PLA2G1BATG4B | |
| SCHEMBL8624680 | 0.82 | GAA (0.45) | ALDH1A1HTR6HTR2A | |
| SCHEMBL8625656 | 0.81 | PGAM1 (0.41) | ALDH1A1BRD4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8626684 | 0.76 | CHRNA7 (0.41) | DRD3APAF1MITF | |
| SCHEMBL8624605 | 0.74 | BRD4 (0.47) | ALDH1A1TDP2NSD2PLA2G1BATG4B | |
| SCHEMBL8626990 | 0.74 | KDM2B (0.37) | DRD3APAF1MITF | |
| SCHEMBL7584797 | 0.72 | HTR6 (0.42) | ALDH1A1TDP2NSD2PLA2G1BATG4B | |
| SCHEMBL8628563 | 0.72 | BRD4 (0.42) | BRD4FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849912-A | Biphenyl derivatives | EISAI CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |