Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 8/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625789 | 0.89 | BRD4 (0.43) | GAAL3MBTL1ALDH1A1HTR6 | |
| SCHEMBL8625881 | 0.87 | BRD4 (0.45) | GAAALDH1A1HTR6 | |
| SCHEMBL8624803 | 0.85 | ALDH1A1 (0.44) | ALDH1A1HTR6 | |
| SCHEMBL8625656 | 0.85 | PGAM1 (0.41) | ALDH1A1 | |
| SCHEMBL8628033 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HTR6HTR2A | |
| SCHEMBL8624822 | 0.80 | BRD4 (0.44) | GAAL3MBTL1ALDH1A1HTR6 | |
| SCHEMBL8626684 | 0.80 | CHRNA7 (0.41) | — | |
| SCHEMBL8624802 | 0.78 | KDM2B (0.39) | — | |
| SCHEMBL8624605 | 0.78 | BRD4 (0.47) | GAAL3MBTL1ALDH1A1 | |
| SCHEMBL8628563 | 0.76 | BRD4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849912-A | Biphenyl derivatives | EISAI CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |