Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695595 | 0.81 | CNR2 (0.72) | MEN1KMT2ACNR2TDP1 | |
| SCHEMBL2822341 | 0.79 | MEN1 (0.57) | MEN1MAPTKMT2ACNR2FFAR2 | |
| SCHEMBL7573699 | 0.79 | FAAH (0.50) | MEN1MAPTKMT2AFFAR2SMYD3 | |
| SCHEMBL6136366 | 0.78 | MEN1 (0.60) | MEN1MAPTKMT2ACNR2FFAR2 | |
| SCHEMBL9849400 | 0.78 | MEN1 (0.62) | MEN1MAPTKMT2ACNR2FFAR2 | |
| SCHEMBL31294341 | 0.75 | EPHX1 (0.53) | MEN1MAPTKMT2ASMYD3EPHX1 | |
| SCHEMBL9625224 | 0.74 | TDP1 (0.54) | MEN1MAPTKMT2ACNR2KDM4E | |
| SCHEMBL23758509 | 0.74 | ALDH1A1 (0.62) | MEN1MAPTKMT2ASMYD3HDAC1 | |
| SCHEMBL1852549 | 0.74 | CNR2 (0.72) | MEN1KMT2ACNR2 | |
| SCHEMBL1856691 | 0.74 | CNR2 (0.72) | MEN1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760023-A | CYCLOHEXYLACETAMIDE DERIVATIVES, AGONIST AT KAPPA OPIOD RECEPTORS, TREATMENT OF ITCHING | ADOLOR CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |