Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418523 | 0.85 | SMYD3 (0.51) | MEN1MAPTKMT2ASMYD3HDAC1 | |
| SCHEMBL7574286 | 0.85 | CNR2 (0.46) | FAAHMAOBKDM4ESMN1; SMN2FFAR2 | |
| SCHEMBL7573224 | 0.83 | CNR2 (0.58) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL7571824 | 0.83 | EPHX2 (0.51) | FAAHALDH1A1POLBUSP2 | |
| SCHEMBL7571045 | 0.83 | GLS (0.45) | MAPTALDH1A1POLBMAOBKDM4E | |
| SCHEMBL6136366 | 0.82 | MEN1 (0.60) | MEN1MAPTKMT2ASMYD3HDAC1 | |
| SCHEMBL7567337 | 0.79 | ELANE (0.48) | MEN1KMT2AHDAC1HDAC8KDM4E | |
| SCHEMBL7570691 | 0.79 | SMN1; SMN2 (0.50) | MEN1MAPTKMT2AALDH1A1HTT | |
| SCHEMBL7569870 | 0.79 | TDP1 (0.58) | FAAHKMT2AALDH1A1HTTKDM4E | |
| SCHEMBL8626174 | 0.79 | MEN1 (0.50) | FAAHMEN1MAPTKMT2ASMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |