Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27795167 | 0.87 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2MAPTGAANPC1 | |
| SCHEMBL28087330 | 0.84 | ALDH1A1 (0.50) | LMNAMAPTGAANPC1RAB9A | |
| SCHEMBL8563438 | 0.84 | RAB9A (0.50) | LMNASMN1; SMN2MAPTGAANPC1 | |
| SCHEMBL9912720 | 0.84 | NPC1 (0.48) | LMNASMN1; SMN2MAPTGAANPC1 | |
| SCHEMBL30069255 | 0.84 | NPC1 (0.48) | LMNASMN1; SMN2MAPTGAANPC1 | |
| SCHEMBL1340160 | 0.78 | NPC1 (0.74) | LMNASMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL8600585 | 0.78 | ESR1 (0.54) | LMNAMAPTRAB9ANPSR1ALDH1A1 | |
| SCHEMBL8626740 | 0.78 | TXNRD1 (0.39) | LMNASMN1; SMN2MAPTGAANPC1 | |
| SCHEMBL1123538 | 0.77 | NPC1 (0.72) | LMNASMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL8581954 | 0.77 | NPC1 (0.72) | LMNASMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |