Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622094 | 0.81 | MEN1 (0.38) | CACNA2D1CACNA1BCACNB1CACNA1CP2RX7 | |
| SCHEMBL10545517 | 0.73 | ALDH1A1 (0.37) | CACNA2D1CACNA1BCACNB1CACNA1CALDH1A1 | |
| SCHEMBL8626971 | 0.72 | POLB (0.38) | ALDH1A1CNR1CNR2MEN1KMT2A | |
| SCHEMBL8625044 | 0.72 | GPBAR1 (0.37) | CACNA2D1CACNA1BCACNB1CACNA1CMEN1 | |
| SCHEMBL10546806 | 0.71 | HTT (0.43) | CACNA2D1CACNA1BCACNB1CACNA1COPRK1 | |
| SCHEMBL8077395 | 0.71 | KMT2A (0.38) | CACNA2D1CACNA1BCACNB1CACNA1COPRM1 | |
| SCHEMBL8082394 | 0.71 | CHRM1 (0.36) | CACNA2D1CACNA1BCACNB1CACNA1CALDH1A1 | |
| SCHEMBL8623693 | 0.71 | ALDH1A1 (0.46) | CACNA2D1CACNA1BCACNB1CACNA1CALDH1A1 | |
| SCHEMBL10540280 | 0.70 | POLB (0.39) | CACNA2D1CACNA1BCACNB1ALDH1A1CNR1 | |
| SCHEMBL10543810 | 0.70 | CNR1 (0.37) | ALDH1A1CNR1CNR2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503597-B1 | Penam derivatives and processes for producing the same | OTSUKA KAGAKU KK (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5599925-A | BACTERICIDES | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| EP-0503597-A2 | Penam derivatives and processes for producing the same | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1992-09-16 | — | — | EP | disclosed |