Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | USP1 | O94782 | 2/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 4/20 | 0.33 |
| ▸ | BMPR1A | P36894 | 4/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 4/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | CDC25C | P30307 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630513 | 0.80 | GSK3B (0.33) | ALDH1A1CYP11B2BMPR1BBMPR1AACVRL1 | |
| SCHEMBL8627908 | 0.80 | ALDH1A1 (0.41) | ALDH1A1TSHRUSP1PKM | |
| SCHEMBL8137963 | 0.79 | HSD17B10 (0.41) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL8629038 | 0.77 | CYP11B2 (0.36) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL30661603 | 0.76 | CYP11B2 (0.36) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL26621580 | 0.76 | CYP11B2 (0.36) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL11922155 | 0.73 | KDM4E (0.36) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL27071821 | 0.73 | ACVRL1 (0.38) | CYP11B2USP1BMPR1BBMPR1AACVRL1 | |
| SCHEMBL8630032 | 0.72 | MAPT (0.38) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL18422666 | 0.72 | LMNA (0.35) | ALDH1A1CYP11B2BMPR1BBMPR1AACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767128-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1998-06-16 | — | — | US | disclosed |
| US-5618819-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1997-04-08 | — | — | US | disclosed |
| EP-0691339-A1 | Amine derivatives of 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-ones and oxazolo(4,5-b)pyridin-2(3H)-ones, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |