Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763079 | 0.82 | ECE1 (0.30) | ECE1 | |
| SCHEMBL18228883 | 0.79 | EPHX1 (0.38) | EPHX1 | |
| SCHEMBL7432362 | 0.79 | EPHX1 (0.38) | EPHX1 | |
| SCHEMBL8762488 | 0.78 | LMNA (0.42) | — | |
| Hydrochloric Acid SCHEMBL7433033 | 0.78 | EPHX1 (0.37) | EPHX1 | |
| SCHEMBL8624798 | 0.76 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL8762407 | 0.76 | L3MBTL1 (0.49) | — | |
| SCHEMBL8762402 | 0.75 | MAPK1 (0.44) | — | |
| SCHEMBL8625002 | 0.72 | ECE1 (0.43) | EPHX1ECE1 | |
| SCHEMBL9554761 | 0.70 | CA1 (0.39) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636142-B1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LTD (GB) | 1998-06-17 | — | — | EP | disclosed |
| EP-0636141-B1 | PYRIMIDINYL ACETAMIDES AS ELASTASE INHIBITORS | ZENECA LTD (GB) | 1997-06-25 | — | — | EP | disclosed |