Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761334 | 0.83 | SMN1; SMN2 (0.40) | HTTSMN1; SMN2ALDH1A1KMT2AMAPK1 | |
| SCHEMBL8762494 | 0.80 | L3MBTL1 (0.50) | L3MBTL1HTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8624798 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8627352 | 0.76 | EPHX1 (0.34) | — | |
| SCHEMBL8762402 | 0.76 | MAPK1 (0.44) | HTTALDH1A1MAPK1RAB9ALMNA | |
| SCHEMBL3716649 | 0.73 | L3MBTL1 (0.64) | L3MBTL1HTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL26310077 | 0.72 | HTT (0.52) | L3MBTL1HTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL1256540 | 0.71 | TAS1R3 (0.56) | L3MBTL1HTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL12156703 | 0.71 | HRH3 (0.57) | L3MBTL1HTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL2755853 | 0.70 | MAPK1 (0.60) | L3MBTL1HTTSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636141-B1 | PYRIMIDINYL ACETAMIDES AS ELASTASE INHIBITORS | ZENECA LTD (GB) | 1997-06-25 | — | — | EP | disclosed |