Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631182 | 0.89 | PTGS2 (0.44) | PTGS2KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL8631646 | 0.88 | SMN1; SMN2 (0.54) | F10PTGS2KMT2AMEN1NPC1 | |
| SCHEMBL8631931 | 0.88 | MEN1 (0.49) | F10KMT2AMEN1SCN9AF2 | |
| SCHEMBL7777871 | 0.87 | PTGS2 (0.58) | PTGS2KMT2AMEN1 | |
| SCHEMBL8629992 | 0.86 | PKM (0.48) | F10PTGS2SCN9ANPC1RAB9A | |
| SCHEMBL8628183 | 0.85 | PTGS2 (0.52) | PTGS2KMT2ASCN9ANPC1RAB9A | |
| SCHEMBL8628679 | 0.85 | MEN1 (0.58) | F10KMT2AMEN1SCN9ARAB9A | |
| SCHEMBL8629361 | 0.84 | TGFBR1 (0.53) | F10SCN9AF2 | |
| SCHEMBL8633944 | 0.84 | F10 (0.48) | F10KMT2AMEN1SCN9AF2 | |
| SCHEMBL8630451 | 0.84 | PTGS2 (0.52) | F10PTGS2KMT2ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |