SCHEMBL8627896

SCHEMBL8627896

Cc1cc(C)c(S(=O)(=O)O)c(C)c1N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.38
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 3/20 0.38
TP53 P04637 2/20 0.37
BRD4 O60885 2/20 0.37
CREBBP Q92793 1/20 0.37
SUMO2 P61956 2/20 0.36
SUMO1 P63165 2/20 0.36
SENP7 Q9BQF6 2/20 0.36
SENP2 Q9HC62 2/20 0.36
SENP1 Q9P0U3 2/20 0.36
SENP3 Q9H4L4 1/20 0.36
F2 P00734 2/20 0.36
PRSS1 P07477 2/20 0.36
PRSS2 P07478 2/20 0.36
PRSS3 P35030 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
POLB P06746 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9280690 0.86 ALDH1A1 (0.36) ALDH1A1KDM4ETP53BRD4CREBBP
SCHEMBL28066593 0.85 F2 (0.37) RAPGEF4ALDH1A1KDM4ETP53BRD4
SCHEMBL2869064 0.84 CA1 (0.41) RAPGEF4KDM4EBRD4F2PRSS1
SCHEMBL8217255 0.83 LMNA (0.40) ALDH1A1KDM4ETP53BRD4CREBBP
Sulfuric Acid SCHEMBL8642015 0.82 ALDH1A1 (0.42) ALDH1A1KDM4ETP53BRD4CREBBP
SCHEMBL6586893 0.81 ALDH1A1 (0.48) RAPGEF4ALDH1A1KDM4ETP53TDP1
SCHEMBL83875 0.80 LMNA (0.39) RAPGEF4ALDH1A1KDM4EF2PRSS1
SCHEMBL10426712 0.80 TP53 (0.39) RAPGEF4ALDH1A1KDM4ETP53BRD4
SCHEMBL2032295 0.79 SENP2 (0.40) RAPGEF4ALDH1A1KDM4ETP53BRD4
Ammonia Solution, Strong SCHEMBL27721988 0.78 LMNA (0.38) RAPGEF4ALDH1A1KDM4EF2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119894866-A YAP/TAZ-TEAD oncoprotein inhibitors 布里奇恩生物科学公司 2025-04-25 CN disclosed
EP-4541794-A1 PHENYL-SUBSTITUTED DIHYDRONAPHTHYRIDINE COMPOUNDS, AND PREPARATION AND USE THEREOF Suzhong Pharmaceutical Group Co., Ltd. (CN) 2025-04-23 EP disclosed
WO-2024208256-A1 TARGETED PROTEIN DEGRADATION COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海汇伦医药股份有限公司 2024-10-10 WO disclosed
EP-1795562-A2 Fiber reactive dyestuffs Everlight USA, Inc. (US) 2007-06-13 EP disclosed
EP-0851004-A1 Disazo dyestuffs for dyeing materials containing cellulose BAYER AG (DE) 1998-07-01 EP disclosed
US-4719053-A FOR DYES HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-12 US disclosed
US-4555400-A AN ETHOXYLATED DIAMINOANTHRAQUINONE COMPOSITION; COSMETICS; DETERGENTS LEVER BROTHERS COMPANY (US) 1985-11-26 US disclosed
US-4540570-A BENZOIC ACID, ANTHROQUINONE DERIVATIVE OF POLYOXYALKYLENEDIAMINE LEVER BROTHERS COMPANY (US) 1985-09-10 US disclosed
EP-0045488-B1 WATER-SOLUBLE FIBRE-REACTIVE COMPOUNDS AND THEIR USE IN FINISHING TEXTILES, AS WELL AS THE BETA-CHLOROETHYL-SULFONYL-METHYL-BENZOIC-ACID HALOGENIDES, AND THEIR USE AS A FIBRE-REACTIVE ANCHOR HOECHST AKTIENGESELLSCHAFT (DE) 1985-06-19 EP disclosed
US-4499071-A MIXTURE OF 2-METHYL-4-ISOTHIAZOLIN-3-ONE AND AMINOANTHRAQUINONE LEVER BROTHERS COMPANY (US) 1985-02-12 US disclosed
US-4473498-A Water-soluble, fiber-reactive organic dyestuffs containing a β-chloro-ethylsulfonyl-methyl-benzoic acid amide group HOECHST AKTIENGESELLSCHAFT (DE) 1984-09-25 US disclosed
US-4454146-A A (BENZ)ISOTHIAZOLONE AND A SUBNSTITUTED ANTHRAQUINONE DYE LEVER BROTHERS COMPANY (US) 1984-06-12 US disclosed
EP-0094721-A1 Synergistic preservative compositions, products containing them and processes for using them UNILEVER N.V. (NL) 1983-11-23 EP disclosed
EP-0012969-B1 WATER-SOLUBLE FIBRE-REACTIVE COMPOUNDS AND THEIR USE IN FIBRE FINISHING,ESPECIALLY AS DYESTUFFS,AND DIHALOGENO-PYRIDAZONYL-CARBOXYLIC AND SULFONIC ACID HALIDES AND THEIR USE AS FIBRE-REACTIVE ANCHORS,AS WELL AS PROCESS FOR THE PREPARATION OF THESE COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1983-06-08 EP disclosed
EP-0045488-A2 Water-soluble fibre-reactive compounds and their use in finishing textiles, as well as the beta-chloroethyl-sulfonyl-methyl-benzoic-acid halogenides, and their use as a fibre-reactive anchor HOECHST AKTIENGESELLSCHAFT (DE) 1982-02-10 EP disclosed
EP-0012969-A2 Water-soluble fibre-reactive compounds and their use in fibre finishing,especially as dyestuffs,and dihalogeno-pyridazonyl-carboxylic and sulfonic acid halides and their use as fibre-reactive anchors,as well as process for the preparation of these compound HOECHST AKTIENGESELLSCHAFT (DE) 1980-07-09 EP disclosed