Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627896 | 0.85 | RAPGEF4 (0.38) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL8217255 | 0.81 | LMNA (0.40) | ALDH1A1TP53TSHRCYP3A4TDP1 | |
| SCHEMBL159033 | 0.77 | L3MBTL1 (0.42) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL2869064 | 0.77 | CA1 (0.41) | F2PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL9280690 | 0.75 | ALDH1A1 (0.36) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| Sulfuric Acid SCHEMBL8642015 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TP53TSHRCYP3A4TDP1 | |
| SCHEMBL10426712 | 0.74 | TP53 (0.39) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL83875 | 0.73 | LMNA (0.39) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| Hydroxyamine SCHEMBL259333 | 0.73 | CA1 (0.54) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL5685409 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TP53TSHRCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103930471-B | Flexible polyamines, flexible amine-terminated adducts, compositions thereof, and methods of use | PRC-DESOTO INTERNATIONAL, INC. (US) | 2016-05-18 | — | — | CN | disclosed |