Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CCNH | P51946 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629978 | 0.93 | MAPT (0.43) | MAPTKMT2AMEN1ALDH1A1FFAR4 | |
| SCHEMBL8631516 | 0.91 | PTGS2 (0.46) | MAPTKMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL8632451 | 0.90 | KDM1A (0.45) | KMT2AMEN1ALDH1A1KDM4EHDAC4 | |
| SCHEMBL8629307 | 0.88 | GAA (0.47) | MAPTNPY5RKMT2AMEN1ALDH1A1 | |
| SCHEMBL8632194 | 0.88 | KMT2A (0.40) | MAPTKMT2AMEN1ALDH1A1PTGS1 | |
| SCHEMBL8631851 | 0.86 | MAPT (0.39) | MAPTKMT2AMEN1ALDH1A1FFAR4 | |
| SCHEMBL8630021 | 0.85 | SMN1; SMN2 (0.49) | MAPTNPY5RCA12CA2CA9 | |
| SCHEMBL8632849 | 0.84 | MAPT (0.39) | MAPTKMT2AMEN1FFAR4PTGS1 | |
| SCHEMBL8629928 | 0.84 | PTGS2 (0.43) | MAPTNPY5RCA12CA9KMT2A | |
| SCHEMBL8629730 | 0.83 | MAPT (0.45) | MAPTNPY5RKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |