Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629978 | 0.90 | MAPT (0.43) | KMT2AMAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8631516 | 0.88 | PTGS2 (0.46) | KMT2AMAPTPOLBNPSR1MEN1 | |
| SCHEMBL8628005 | 0.88 | MAPT (0.47) | KMT2AMAPTALDH1A1NPY5RMEN1 | |
| SCHEMBL8632451 | 0.87 | KDM1A (0.45) | KMT2APOLBALDH1A1NPSR1MEN1 | |
| SCHEMBL8634609 | 0.86 | KMT2A (0.45) | GAAKMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL8632194 | 0.85 | KMT2A (0.40) | GAAKMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL8631438 | 0.85 | CYP1A2 (0.46) | GAAKMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL8634385 | 0.85 | ACLY (0.42) | GAAKMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL8629545 | 0.85 | NPC1 (0.41) | SMN1; SMN2ALDH1A1CYP2C9LMNA | |
| SCHEMBL8631639 | 0.84 | KMT2A (0.41) | GAAKMT2AMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |