SCHEMBL86283

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL91673	0.86	ALDH1A1 (0.55)	AKR1B1LMNAMAPK14ACHENOTUM
	SCHEMBL86282	0.81	AKR1B1 (0.46)	HSD17B3AKR1B1MAPK14ACHENOTUM
	SCHEMBL86279	0.78	ACHE (0.59)	AKR1B1LMNAMAPK14ACHENOTUM
	SCHEMBL31123671	0.78	ACHE (0.59)	AKR1B1LMNAMAPK14ACHENOTUM
	SCHEMBL31510701	0.78	ACHE (0.59)	AKR1B1LMNAMAPK14ACHENOTUM
	SCHEMBL13871237	0.78	NPC1 (0.51)	AKR1B1LMNAHTTNPSR1PARP1
	SCHEMBL86330	0.78	TDP1 (0.59)	HSD17B3AKR1B1PARP1PARP10MAPK14
	SCHEMBL86749	0.78	MAOB (0.54)	HSD17B3AKR1B1GAAHTTMAPK14
	SCHEMBL86333	0.78	AKR1B1 (0.46)	AKR1B1LMNAMAPK14ACHENOTUM
	SCHEMBL86191	0.78	ELANE (0.51)	HSD17B3AKR1B1HTTMAPK14ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.