Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.36 |
| ▸ | BRAF | P15056 | 5/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624802 | 0.88 | KDM2B (0.39) | KDM2BAPAF1CHRNA7DRD3HRH3 | |
| SCHEMBL8627347 | 0.87 | MITF (0.39) | APAF1BRAFCHRNA7DRD3HRH3 | |
| SCHEMBL8624900 | 0.87 | APAF1 (0.38) | APAF1BRAFCHRNA7DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL8625633 | 0.86 | BRD4 (0.38) | APAF1BRAFCHRNA7DRD3HRH3 | |
| SCHEMBL8627903 | 0.84 | APAF1 (0.36) | APAF1BRAFCHRNA7DRD3DRD2 | |
| SCHEMBL8624540 | 0.82 | PGAM1 (0.40) | KDM2BAPAF1CHRNA7MITFPARP14 | |
| SCHEMBL8630282 | 0.81 | PGAM1 (0.39) | APAF1CHRNA7DRD3HRH3MITF | |
| SCHEMBL8630208 | 0.81 | KDM2B (0.41) | KDM2BBRAFHTR6BRD4 | |
| SCHEMBL8626684 | 0.80 | CHRNA7 (0.41) | KDM2BAPAF1CHRNA7DRD3DRD2 | |
| SCHEMBL8629280 | 0.79 | MITF (0.41) | KDM2BAPAF1CHRNA7DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849912-A | Biphenyl derivatives | EISAI CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |