Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 14/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629705 | 0.89 | PTGIR (0.43) | F10F2 | |
| SCHEMBL8630931 | 0.88 | F10 (0.39) | MEN1KMT2AF10F2 | |
| SCHEMBL8631461 | 0.87 | PTGS2 (0.49) | F10F2 | |
| SCHEMBL8627604 | 0.87 | PTGS2 (0.41) | F10F2 | |
| SCHEMBL8628679 | 0.87 | MEN1 (0.58) | MEN1KMT2AF10SCN9AF2 | |
| SCHEMBL8631931 | 0.86 | MEN1 (0.49) | MEN1KMT2AF10SCN9AF2 | |
| SCHEMBL7780139 | 0.85 | MEN1 (0.58) | MEN1KMT2AMAPKAPK2 | |
| SCHEMBL8634386 | 0.84 | PTGS2 (0.50) | F10P2RX3 | |
| SCHEMBL8627595 | 0.83 | F10 (0.48) | MEN1KMT2AF10SCN9AF2 | |
| SCHEMBL8629361 | 0.82 | TGFBR1 (0.53) | F10SCN9AF2MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |