Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631571 | 0.88 | KMO (0.47) | MEN1KMT2ATDP1KMOCHUK | |
| SCHEMBL8627990 | 0.83 | HPGD (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8632682 | 0.82 | KDM1A (0.46) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL8630483 | 0.82 | KMT2A (0.42) | PTGS2SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL8634847 | 0.81 | NAT1 (0.46) | MEN1KMT2AMAPTLMNALRRK2 | |
| SCHEMBL8634594 | 0.81 | FFAR4 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL8629976 | 0.81 | L3MBTL1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8629853 | 0.80 | MEN1 (0.45) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL8627699 | 0.80 | MAPK14 (0.40) | PTGS2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8630886 | 0.79 | MCL1 (0.45) | ALDH1A1MEN1KMT2ATDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |