Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | GYS1 | P13807 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | S100A9 | P06702 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.39 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628728 | 0.88 | CCR2 (0.39) | KMOGYS1CHUKMEN1KMT2A | |
| SCHEMBL8632682 | 0.87 | KDM1A (0.46) | GYS1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL8634847 | 0.87 | NAT1 (0.46) | MEN1KMT2ALRRK2L3MBTL1 | |
| SCHEMBL8629976 | 0.86 | L3MBTL1 (0.51) | GYS1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL8630483 | 0.85 | KMT2A (0.42) | KMOMEN1KMT2ATDP1KDM4E | |
| SCHEMBL8634594 | 0.84 | FFAR4 (0.39) | MEN1KMT2ATDP1LRRK2L3MBTL1 | |
| SCHEMBL8631355 | 0.84 | L3MBTL1 (0.44) | GYS1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL8628709 | 0.83 | ERBB2 (0.40) | PTGES2MEN1KMT2ATDP1S100A9 | |
| SCHEMBL8634943 | 0.83 | MAP2K4 (0.44) | MEN1KMT2AMAP2K4LRRK2L3MBTL1 | |
| SCHEMBL8759028 | 0.83 | PKM (0.39) | KMOCHUKPTGES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |