Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629976 | 0.88 | L3MBTL1 (0.51) | LMNAMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8634943 | 0.88 | MAP2K4 (0.44) | PGRMEN1KMT2AIDH2KAT6A | |
| SCHEMBL8632682 | 0.87 | KDM1A (0.46) | NAT1KDM1ALMNAMAPTMEN1 | |
| SCHEMBL8631571 | 0.87 | KMO (0.47) | MEN1KMT2AL3MBTL1LRRK2 | |
| SCHEMBL8630886 | 0.87 | MCL1 (0.45) | MEN1KMT2AL3MBTL1LRRK2HDAC4 | |
| SCHEMBL8628709 | 0.83 | ERBB2 (0.40) | PGRLMNAMAPTMEN1KMT2A | |
| SCHEMBL8629094 | 0.83 | ERBB2 (0.40) | PGRLMNAMAPTMEN1KMT2A | |
| SCHEMBL8634594 | 0.82 | FFAR4 (0.39) | LMNAMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8628831 | 0.81 | LRRK2 (0.50) | LMNAMAPTMEN1KMT2AIDH2 | |
| SCHEMBL8631355 | 0.81 | L3MBTL1 (0.44) | MAPTMEN1KMT2AL3MBTL1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |