Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646200 | 0.88 | ALDH1A1 (0.33) | ALDH1A1ALOX15HSD17B10KDM4EHPGD | |
| SCHEMBL8647722 | 0.88 | ALDH1A1 (0.33) | ALDH1A1ALOX15HSD17B10KDM4EHPGD | |
| SCHEMBL8645169 | 0.82 | PGR (0.32) | CA2CA9CA12TDP1LMNA | |
| SCHEMBL8628798 | 0.82 | APP (0.44) | ALDH1A1ALOX15HSD17B10KDM4EHPGD | |
| SCHEMBL5408498 | 0.81 | GAA (0.42) | ALDH1A1ALOX15HSD17B10KDM4EHPGD | |
| SCHEMBL8651665 | 0.80 | PSEN1 (0.43) | ALDH1A1CA2CA9CA12MEN1 | |
| SCHEMBL2895868 | 0.79 | PKM (0.48) | ALDH1A1CA2CA9CA12NPC1 | |
| SCHEMBL384539 | 0.78 | CA1 (0.46) | ALDH1A1HSD17B10KDM4EHPGDCA2 | |
| SCHEMBL7541154 | 0.78 | ALDH1A1 (0.56) | ALDH1A1ALOX15HSD17B10KDM4EHPGD | |
| SCHEMBL5408521 | 0.77 | CA2 (0.48) | ALDH1A1KDM4EHPGDCA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705702-A | REACTING AN ARYL GRIGNARD REAGENT WITH THIONYL CHLORIDE, THEN WITH TRIORGANOSILYL SULFONATE OR TRIORGANOSILYLHALIDE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |