Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140065 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HSD17B10ALOX15KDM4EHPGD | |
| SCHEMBL8629128 | 0.82 | ALDH1A1 (0.41) | ALDH1A1HSD17B10ALOX15KDM4EHPGD | |
| SCHEMBL503950 | 0.81 | ACHE (0.50) | ALDH1A1TP53KMT2ACA9MEN1 | |
| SCHEMBL2964009 | 0.81 | ACHE (0.50) | ALDH1A1TP53KMT2ACA9MEN1 | |
| SCHEMBL6140890 | 0.81 | CA2 (0.43) | ALDH1A1HSD17B10ALOX15KDM4EHPGD | |
| SCHEMBL6140387 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HSD17B10ALOX15KDM4EHPGD | |
| SCHEMBL2955282 | 0.79 | KMT2A (0.49) | FFAR1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL2960247 | 0.78 | PKM (0.50) | ALDH1A1LMNACA2CA1TDP1 | |
| SCHEMBL3137415 | 0.75 | KMT2A (0.46) | LMNAKMT2ACA9MEN1CA12 | |
| SCHEMBL1002297 | 0.75 | KMT2A (0.46) | LMNAKMT2ACA9MEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705702-A | REACTING AN ARYL GRIGNARD REAGENT WITH THIONYL CHLORIDE, THEN WITH TRIORGANOSILYL SULFONATE OR TRIORGANOSILYLHALIDE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |