SCHEMBL8629183

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14557028	0.74	HSD11B1 (0.34)	ALDH1A1DRD2
	SCHEMBL1544604	0.73	NPC1 (0.51)	CYP1A2ALDH1A1HSD17B10MEN1CYP2C19
	SCHEMBL392717	0.73	HSD11B1 (0.53)	ALDH1A1KMT2ADRD2
	SCHEMBL1543914	0.72	SMN1; SMN2 (0.46)	CYP1A2ALDH1A1MEN1CYP3A4CYP2C19
	SCHEMBL14557023	0.72	LMNA (0.42)	ALDH1A1MEN1KMT2ADRD2
	SCHEMBL20514084	0.70	ACHE (0.45)	CYP1A2ALOX15ALDH1A1HSD17B10CYP2D6
	SCHEMBL4184528	0.70	HSD11B1 (0.43)	CYP1A2ALDH1A1MEN1CYP2C19KMT2A
	Hydrochloric Acid SCHEMBL4869761	0.70	SMN1; SMN2 (0.45)	CYP1A2ALDH1A1MEN1CYP3A4CYP2C19
	SCHEMBL12803376	0.70	ALDH1A1 (0.45)	ALOX15ALDH1A1HSD17B10ACHEMEN1
	SCHEMBL1544137	0.70	HSD11B1 (0.56)	ALDH1A1HSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.