Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP1 | P07148 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.40 |
| ▸ | FEN1 | P39748 | 7/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627988 | 0.88 | CA2 (0.38) | ALOX5APFEN1CA2CA1CA12 | |
| SCHEMBL8627632 | 0.86 | CA1 (0.42) | CA2CA1CA12CA9 | |
| SCHEMBL8632667 | 0.86 | CA4 (0.40) | ALOX5APFEN1CA2CA1PTGES2 | |
| SCHEMBL7773297 | 0.82 | MAP2K7 (0.52) | CA2CA1CA12CA9 | |
| SCHEMBL8631181 | 0.81 | PTGS2 (0.50) | ALOX5APFEN1TRPV1CA9 | |
| SCHEMBL8629397 | 0.81 | ALOX5AP (0.40) | ALOX5APFEN1CA2CA1PTGES2 | |
| SCHEMBL8629486 | 0.81 | ALOX5AP (0.44) | ALOX5APFEN1TRPV1CA2PTGES2 | |
| SCHEMBL8632812 | 0.80 | ALOX5AP (0.47) | ALOX5APFEN1TRPV1 | |
| SCHEMBL8630031 | 0.78 | PTGS2 (0.41) | ALOX5APFEN1TRPV1CA2CA1 | |
| SCHEMBL8629939 | 0.77 | MAPT (0.47) | FABP1ALOX5APFEN1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |