Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 11/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651447 | 0.87 | GPR35 (0.42) | ABCG2ABCB1MAPTSMN1; SMN2HTT | |
| SCHEMBL8630118 | 0.83 | PIK3CD (0.41) | ABCG2ABCB1MAPTSMN1; SMN2HTT | |
| SCHEMBL8632527 | 0.81 | ALDH1A1 (0.43) | ABCG2ABCB1MAPTSMN1; SMN2HTT | |
| SCHEMBL8632270 | 0.80 | L3MBTL1 (0.48) | ABCG2ABCB1SMN1; SMN2ALDH1A1GPR35 | |
| SCHEMBL5193130 | 0.75 | MAPT (0.48) | ABCG2ABCB1MAPTSMN1; SMN2HTT | |
| SCHEMBL8631751 | 0.73 | ALDH1A1 (0.47) | MAPTSMN1; SMN2HTTRAB9AALDH1A1 | |
| SCHEMBL8630090 | 0.72 | NTRK1 (0.46) | ABCG2ABCB1MAPTSMN1; SMN2HTT | |
| SCHEMBL8540029 | 0.72 | MAPT (0.48) | ABCG2MAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8628783 | 0.71 | RAB9A (0.49) | ABCG2MAPTSMN1; SMN2HTTRAB9A | |
| SCHEMBL8794497 | 0.71 | HSD17B10 (0.38) | SMN1; SMN2HTTRAB9APAX8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847126-A | N-azinyl-N'-(het) arylsulphonyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| US-5580842-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| US-5476936-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-19 | — | — | US | disclosed |