Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632078 | 0.91 | AVPR1A (0.42) | AVPR2AVPR1AHSD11B1AVPR1BLMNA | |
| SCHEMBL8634000 | 0.87 | AVPR1A (0.41) | AVPR2AVPR1AHSD11B1AVPR1B | |
| SCHEMBL8634665 | 0.86 | AVPR2 (0.41) | AVPR2AVPR1AHSD11B1KDM4EGAA | |
| SCHEMBL8631785 | 0.77 | ABCB1 (0.38) | AVPR2AVPR1AHSD11B1LMNAESR1 | |
| Hydrochloric Acid SCHEMBL8661682 | 0.77 | LMNA (0.44) | AVPR2AVPR1AHSD11B1AVPR1BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8634039 | 0.76 | LMNA (0.45) | AVPR2AVPR1AHSD11B1AVPR1BSMN1; SMN2 | |
| SCHEMBL8631725 | 0.73 | AVPR2 (0.40) | AVPR2AVPR1AHSD11B1AVPR1BLMNA | |
| SCHEMBL8632028 | 0.73 | GRM4 (0.41) | AVPR2AVPR1AAVPR1BSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8661678 | 0.72 | AVPR2 (0.52) | AVPR2AVPR1AHSD11B1SMN1; SMN2LMNA | |
| SCHEMBL8632578 | 0.72 | AVPR2 (0.44) | AVPR2AVPR1AHSD11B1AVPR1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |