Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 10/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630006 | 0.77 | AVPR2 (0.42) | AVPR2LMNAHSD11B1AVPR1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8661682 | 0.73 | LMNA (0.44) | AVPR2LMNAHSD11B1AVPR1AALDH1A1 | |
| SCHEMBL8631780 | 0.73 | ALDH1A1 (0.38) | ABCB1ABCG2AVPR2LMNAAVPR1A | |
| Hydrochloric Acid SCHEMBL8634039 | 0.73 | LMNA (0.45) | AVPR2LMNAHSD11B1AVPR1AALDH1A1 | |
| SCHEMBL8632078 | 0.70 | AVPR1A (0.42) | AVPR2LMNAHSD11B1AVPR1ATP53 | |
| SCHEMBL8632578 | 0.69 | AVPR2 (0.44) | AVPR2LMNAHSD11B1AVPR1ATP53 | |
| Hydrochloric Acid SCHEMBL8632564 | 0.69 | AVPR2 (0.46) | AVPR2AVPR1A | |
| Hydrochloric Acid SCHEMBL8631933 | 0.68 | AVPR2 (0.47) | AVPR2LMNAAVPR1ATP53 | |
| SCHEMBL8634000 | 0.67 | AVPR1A (0.41) | AVPR2HSD11B1AVPR1A | |
| Hydrochloric Acid SCHEMBL8632123 | 0.67 | AVPR2 (0.45) | AVPR2LMNAAVPR1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |