Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634000 | 0.87 | AVPR1A (0.41) | AVPR2AVPR1AHSD11B1 | |
| SCHEMBL8632078 | 0.86 | AVPR1A (0.42) | AVPR2AVPR1AHSD11B1 | |
| SCHEMBL8630006 | 0.86 | AVPR2 (0.42) | AVPR2AVPR1AHSD11B1KDM4EGAA | |
| SCHEMBL8635113 | 0.67 | CHRM5 (0.42) | AVPR2AVPR1AKDM4E | |
| SCHEMBL8627393 | 0.67 | AVPR1A (0.40) | AVPR2AVPR1AHSD11B1 | |
| SCHEMBL8627408 | 0.67 | AVPR1A (0.40) | AVPR2AVPR1AHSD11B1 | |
| SCHEMBL8628617 | 0.67 | AVPR1A (0.40) | AVPR2AVPR1A | |
| SCHEMBL8714665 | 0.67 | HSD11B1 (0.43) | AVPR2AVPR1AGRM4HSD11B1 | |
| SCHEMBL8631000 | 0.66 | AVPR1A (0.39) | AVPR2AVPR1AHSD11B1 | |
| SCHEMBL8628507 | 0.66 | AVPR1A (0.39) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |