Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 5/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630006 | 0.91 | AVPR2 (0.42) | AVPR1AAVPR2HSD11B1CHRM3AVPR1B | |
| SCHEMBL8634000 | 0.87 | AVPR1A (0.41) | AVPR1AAVPR2HSD11B1AVPR1BWDR5 | |
| SCHEMBL8634665 | 0.86 | AVPR2 (0.41) | AVPR1AAVPR2HSD11B1 | |
| SCHEMBL8635113 | 0.71 | CHRM5 (0.42) | AVPR1AAVPR2CHRM3AVPR1BWDR5 | |
| SCHEMBL8631725 | 0.71 | AVPR2 (0.40) | AVPR1AAVPR2HSD11B1CHRM3AVPR1B | |
| SCHEMBL8631785 | 0.70 | ABCB1 (0.38) | AVPR1AAVPR2HSD11B1LMNATP53 | |
| Hydrochloric Acid SCHEMBL8634039 | 0.70 | LMNA (0.45) | AVPR1AAVPR2HSD11B1CHRM3AVPR1B | |
| SCHEMBL8628617 | 0.70 | AVPR1A (0.40) | AVPR1AAVPR2AVPR1BWDR5LMNA | |
| Hydrochloric Acid SCHEMBL8661682 | 0.70 | LMNA (0.44) | AVPR1AAVPR2HSD11B1CHRM3AVPR1B | |
| SCHEMBL8632578 | 0.69 | AVPR2 (0.44) | AVPR1AAVPR2HSD11B1CHRM3AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |