Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SDHB | P21912 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633920 | 0.89 | FFAR4 (0.44) | MAPTFFAR4LMNAHTTCYTH2 | |
| SCHEMBL8629936 | 0.88 | MAPK14 (0.42) | FFAR4LMNACYTH2MEN1KMT2A | |
| SCHEMBL8635286 | 0.86 | NAT1 (0.44) | MAPTNPSR1FFAR4LMNAHTT | |
| SCHEMBL8629976 | 0.84 | L3MBTL1 (0.51) | MAPTNPSR1FFAR4LMNAMEN1 | |
| SCHEMBL8629853 | 0.83 | MEN1 (0.45) | MAPTFFAR4LMNAMEN1KMT2A | |
| SCHEMBL8634594 | 0.83 | FFAR4 (0.39) | MAPTFFAR4LMNAHTTPOLB | |
| SCHEMBL8627699 | 0.81 | MAPK14 (0.40) | FFAR4LMNACYTH2MEN1KMT2A | |
| SCHEMBL8630886 | 0.81 | MCL1 (0.45) | FFAR4HTTMEN1KMT2ATDP1 | |
| SCHEMBL8758733 | 0.80 | MAP2K4 (0.39) | MAPTFFAR4MEN1KMT2A | |
| SCHEMBL8629284 | 0.80 | CCR4 (0.39) | MAPTFFAR4LMNAHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |