Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CCNH | P51946 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629936 | 0.90 | MAPK14 (0.42) | FFAR4MEN1KMT2ATDP1CYTH2 | |
| SCHEMBL8759537 | 0.89 | MAPT (0.40) | FFAR4MAPTALDH1A1LMNA | |
| SCHEMBL8630116 | 0.89 | MAPT (0.39) | FFAR4MEN1KMT2ATDP1MAPT | |
| SCHEMBL8758733 | 0.87 | MAP2K4 (0.39) | FFAR4MEN1KMT2AHTR6MAPT | |
| SCHEMBL8629853 | 0.84 | MEN1 (0.45) | FFAR4MEN1KMT2ATDP1HTR6 | |
| SCHEMBL8630886 | 0.83 | MCL1 (0.45) | FFAR4MEN1KMT2ATDP1HTR6 | |
| SCHEMBL8634594 | 0.81 | FFAR4 (0.39) | FFAR4MEN1KMT2ATDP1MAPT | |
| SCHEMBL8629094 | 0.80 | ERBB2 (0.40) | MEN1KMT2ATDP1MAPTMAPK1 | |
| SCHEMBL8629976 | 0.80 | L3MBTL1 (0.51) | FFAR4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8635286 | 0.80 | NAT1 (0.44) | FFAR4MEN1KMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |