Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MAP2K4 | P45985 | 5/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8758733 | 0.92 | MAP2K4 (0.39) | MAPK14MAP2K4MAP2K7FFAR4MEN1 | |
| SCHEMBL8633920 | 0.90 | FFAR4 (0.44) | FFAR4TSHRMEN1KMT2ATDP1 | |
| SCHEMBL8759537 | 0.88 | MAPT (0.40) | MAPK14MAP2K4FFAR4ALDH1A1LMNA | |
| SCHEMBL8630116 | 0.88 | MAPT (0.39) | RXFP1FFAR4TSHRMEN1KMT2A | |
| SCHEMBL8630531 | 0.87 | MAPT (0.45) | MAPK14MAP2K4ALDH1A1LMNA | |
| SCHEMBL8631355 | 0.82 | L3MBTL1 (0.44) | MAPK14MAP2K4RXFP1MAP2K7MEN1 | |
| SCHEMBL8634943 | 0.81 | MAP2K4 (0.44) | MAPK14MAP2K4MAP2K7MEN1KMT2A | |
| SCHEMBL8627699 | 0.81 | MAPK14 (0.40) | MAPK14MAP2K4FFAR4TSHRMEN1 | |
| SCHEMBL8634594 | 0.81 | FFAR4 (0.39) | MAPK14FFAR4TSHRMEN1KMT2A | |
| SCHEMBL8629094 | 0.80 | ERBB2 (0.40) | RXFP1MEN1KMT2ATDP1SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |