Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | S100A9 | P06702 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628709 | 0.89 | ERBB2 (0.40) | KDM4ERXFP1NPSR1MEN1KMT2A | |
| SCHEMBL8629094 | 0.89 | ERBB2 (0.40) | KDM4ERXFP1NPSR1MEN1KMT2A | |
| SCHEMBL8630116 | 0.86 | MAPT (0.39) | KDM4ERXFP1NPSR1MEN1KMT2A | |
| SCHEMBL8629976 | 0.84 | L3MBTL1 (0.51) | KDM4ERXFP1NPSR1MEN1KMT2A | |
| SCHEMBL8632682 | 0.83 | KDM1A (0.46) | NAT1KDM4ERXFP1NPSR1MEN1 | |
| SCHEMBL8631571 | 0.83 | KMO (0.47) | KDM4ERXFP1NPSR1MEN1KMT2A | |
| SCHEMBL8634847 | 0.81 | NAT1 (0.46) | NAT1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL8759028 | 0.80 | PKM (0.39) | MEN1KMT2ATDP1GAAL3MBTL1 | |
| SCHEMBL8633920 | 0.80 | FFAR4 (0.44) | MEN1KMT2ATDP1LMNAALDH1A1 | |
| SCHEMBL8628831 | 0.80 | LRRK2 (0.50) | KDM4ERXFP1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |