Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 7/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 7/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 7/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627190 | 0.91 | AVPR2 (0.42) | POLBTP53KMT2AMAPT | |
| SCHEMBL8634053 | 0.87 | AVPR2 (0.41) | POLBTP53KMT2AMAPT | |
| SCHEMBL8630162 | 0.86 | TSHR (0.38) | TSHRALDH1A1HTTPOLBLMNA | |
| SCHEMBL8631906 | 0.85 | RORC (0.44) | ALDH1A1HTTPOLBLMNAKDM4E | |
| SCHEMBL8633374 | 0.82 | AVPR2 (0.52) | ALDH1A1HTTLMNAPDK1PDK2 | |
| SCHEMBL4686263 | 0.81 | HTR4 (0.34) | TSHRALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL8627538 | 0.80 | KCNMA1 (0.36) | ALDH1A1HTTPOLBLMNATP53 | |
| SCHEMBL8630767 | 0.80 | AVPR2 (0.41) | TSHRALDH1A1POLBTP53KMT2A | |
| SCHEMBL8629474 | 0.78 | AVPR2 (0.51) | LMNAPDK1PDK2PDK3PDK4 | |
| SCHEMBL8630395 | 0.78 | PDK1 (0.35) | TSHRALDH1A1HTTLMNAPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |