Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629617 | 0.90 | ALDH1A1 (0.41) | POLBALOX5ALDH1A1LMNAKMT2A | |
| SCHEMBL8635706 | 0.90 | MAPT (0.40) | POLBALOX5ALDH1A1MAPTPKM | |
| SCHEMBL8632233 | 0.82 | CETP (0.39) | POLBALOX5ALDH1A1LMNAKMT2A | |
| SCHEMBL8632565 | 0.82 | MAPT (0.39) | POLBALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL8748380 | 0.80 | POLB (0.38) | POLBALOX5ALDH1A1KMT2AMAPT | |
| SCHEMBL8659550 | 0.79 | POLB (0.50) | POLBALOX5ALDH1A1LMNAKMT2A | |
| SCHEMBL8632586 | 0.77 | POLB (0.35) | POLBALOX5ALDH1A1MAPTNPSR1 | |
| SCHEMBL8636072 | 0.75 | ALOX5 (0.39) | POLBALOX5ALDH1A1LMNAMAPT | |
| SCHEMBL8632573 | 0.74 | KDM4E (0.39) | POLBLMNAKMT2AMAPTHTT | |
| SCHEMBL8632136 | 0.70 | ALDH1A1 (0.49) | POLBALOX5ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761214-A2 | N,N-disubstituted anilines or alkylamines as singlet oxygen quenchers, topical compositions comprising them | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |