Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629617 | 0.85 | ALDH1A1 (0.41) | PDGFRBPDGFRAPOLBKMT2AMEN1 | |
| SCHEMBL8635317 | 0.84 | PDGFRB (0.42) | PDGFRBPDGFRAPOLBALDH1A1KDM4E | |
| SCHEMBL8635706 | 0.82 | MAPT (0.40) | CETPPOLBALDH1A1PKMTSHR | |
| SCHEMBL8630284 | 0.82 | POLB (0.39) | POLBKMT2AALDH1A1PKMTSHR | |
| SCHEMBL8748380 | 0.75 | POLB (0.38) | POLBKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL8632586 | 0.73 | POLB (0.35) | POLBALDH1A1PKMTSHRMAPK1 | |
| SCHEMBL8628489 | 0.71 | EGFR (0.44) | PDGFRBPDGFRAPOLBKMT2AMEN1 | |
| SCHEMBL8636072 | 0.68 | ALOX5 (0.39) | POLBALDH1A1KDM4EPKMTSHR | |
| SCHEMBL20871931 | 0.66 | TUBB4A (0.47) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL8632136 | 0.66 | ALDH1A1 (0.49) | PDGFRBPDGFRAPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761214-A2 | N,N-disubstituted anilines or alkylamines as singlet oxygen quenchers, topical compositions comprising them | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |