Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630284 | 0.90 | POLB (0.39) | ALDH1A1LMNAMAPTPOLBALOX5 | |
| SCHEMBL8635706 | 0.88 | MAPT (0.40) | ALDH1A1MAPTPOLBALOX5HPGD | |
| SCHEMBL8632233 | 0.85 | CETP (0.39) | ALDH1A1LMNAKDM4EPOLBPDGFRB | |
| SCHEMBL8632136 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTKDM4EESR2 | |
| SCHEMBL8748380 | 0.78 | POLB (0.38) | ALDH1A1MAPTPOLBALOX5HPGD | |
| SCHEMBL8632586 | 0.75 | POLB (0.35) | ALDH1A1MAPTPOLBALOX5HPGD | |
| SCHEMBL8629892 | 0.74 | KDM4E (0.44) | KDM4EPOLBNPC1MEN1KMT2A | |
| SCHEMBL8748519 | 0.73 | CNR1 (0.49) | ALDH1A1LMNAMAPTKDM4EESR2 | |
| SCHEMBL8636072 | 0.73 | ALOX5 (0.39) | ALDH1A1LMNAMAPTKDM4EPOLB | |
| SCHEMBL8633500 | 0.72 | CNR2 (0.47) | LMNAKDM4EPOLBNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |