Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.44 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718172 | 0.82 | AVPR2 (0.43) | AVPR1AAVPR2 | |
| SCHEMBL8716101 | 0.81 | AVPR2 (0.49) | AVPR1AAVPR2AVPR1BCHRM1 | |
| SCHEMBL8632229 | 0.77 | AVPR1A (0.47) | HSD11B1AVPR1AAVPR2AVPR1BCHRM5 | |
| SCHEMBL4682239 | 0.76 | LMNA (0.48) | AVPR1AAVPR2AVPR1BCHRM5CHRM1 | |
| SCHEMBL8713819 | 0.70 | HSD11B1 (0.49) | HSD11B1AVPR1AAVPR2AVPR1BSMO | |
| SCHEMBL8713384 | 0.70 | HSD11B1 (0.48) | HSD11B1AVPR1AAVPR2AVPR1BSMO | |
| SCHEMBL8717630 | 0.70 | AVPR1A (0.57) | HSD11B1AVPR1AAVPR2AVPR1BCHRM1 | |
| SCHEMBL8716136 | 0.69 | AVPR1A (0.47) | HSD11B1AVPR1AAVPR2AVPR1BCHRM1 | |
| SCHEMBL22871480 | 0.68 | AVPR1A (0.49) | AVPR1AAVPR2AVPR1B | |
| SCHEMBL4684883 | 0.67 | AVPR1A (0.54) | HSD11B1AVPR1AAVPR2AVPR1BCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |