Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL506452 | 0.75 | KDM4E (0.41) | ALDH1A1KDM4EALOX15LMNANPSR1 | |
| SCHEMBL8630797 | 0.75 | NPC1 (0.51) | KDM4EPOLBSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL8631451 | 0.75 | GAA (0.51) | ALDH1A1POLBSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL8630229 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KDM4ENPSR1POLBRAB9A | |
| SCHEMBL4949422 | 0.73 | LMNA (0.43) | ALDH1A1KDM4EALOX15LMNANPSR1 | |
| SCHEMBL12622649 | 0.73 | POLB (0.52) | ALDH1A1KDM4ELMNANPSR1POLB | |
| SCHEMBL8633756 | 0.72 | KMT2A (0.37) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL3056218 | 0.72 | KDM4E (0.42) | ALDH1A1KDM4EALOX15LMNANPSR1 | |
| SCHEMBL8626891 | 0.71 | KMT2A (0.31) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL5868810 | 0.70 | LMNA (0.45) | ALDH1A1KDM4EALOX15LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |