Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630479 | 0.92 | CCR4 (0.41) | PTGS2PI4KBHTR6PPARAPTGS1 | |
| SCHEMBL8629095 | 0.90 | MAPT (0.39) | PTGS2PI4KBHTR6PPARAPTGS1 | |
| SCHEMBL8635623 | 0.87 | PI4KB (0.44) | PTGS2PI4KBHTR6KDRPTGS1 | |
| SCHEMBL8632815 | 0.87 | PTGS2 (0.38) | PTGS2PI4KBHTR6PPARAPTGS1 | |
| SCHEMBL8632809 | 0.85 | PI4KB (0.42) | PTGS2PI4KBHTR6ADRB2ADRB1 | |
| SCHEMBL8632918 | 0.85 | PI4KB (0.41) | PTGS2PI4KBHTR6ADRB2ADRB1 | |
| SCHEMBL8630562 | 0.84 | CCR4 (0.42) | PTGS2PI4KBPPARAPTGS1TP53 | |
| SCHEMBL8632826 | 0.84 | PTGS2 (0.46) | PTGS2MAPTTP53 | |
| SCHEMBL8634716 | 0.84 | PI4KB (0.42) | PTGS2PI4KBHTR6KDRPTGS1 | |
| SCHEMBL8631464 | 0.83 | PI4KB (0.40) | PTGS2PI4KBHTR6ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |