Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.53 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7504001 | 0.90 | MAOA (0.56) | PTPRCPTPN1PARP1PARP2PBRM1 | |
| SCHEMBL8635759 | 0.90 | PTPRC (0.53) | PTPRCPTPN1PARP1PARP2PBRM1 | |
| SCHEMBL8633556 | 0.87 | HSD17B1 (0.60) | PTPRCPTPN1PARP1PARP2HSD17B1 | |
| SCHEMBL7180348 | 0.79 | MEN1 (0.56) | PBRM1HSD17B1BRD4CYP2A6MAOA | |
| SCHEMBL8072264 | 0.78 | HRH3 (0.54) | PTPRCPTPN1PARP1PARP2HSD17B1 | |
| SCHEMBL8635876 | 0.78 | HSD17B1 (0.56) | PTPRCPTPN1PARP1PARP2HSD17B1 | |
| SCHEMBL16821228 | 0.77 | PARP10 (0.52) | PTPN1PBRM1HSD17B1BRD4HRH3 | |
| SCHEMBL8632720 | 0.76 | PTPRC (0.48) | PTPRCPTPN1PARP1PARP2HRH3 | |
| SCHEMBL8636444 | 0.74 | PARP1 (0.48) | PTPRCPTPN1PARP1PARP2HRH3 | |
| SCHEMBL8636464 | 0.74 | PTPRC (0.46) | PTPRCPTPN1PARP1PARP2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601191-B1 | NOVEL TETRACYCLIC COMPOUND | KYOWA HAKKO KOGYO KK (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5371225-A | Immunosuppressants | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0601191-A1 | NOVEL TETRACYCLIC COMPOUND | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1994-06-15 | — | — | EP | disclosed |