Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.41 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759075 | 0.91 | MCL1 (0.41) | MAPK14RXFP1FFAR4TSHRMAP2K4 | |
| SCHEMBL8627985 | 0.88 | FFAR4 (0.50) | FFAR4TSHRCYTH2KDM4E | |
| SCHEMBL8759199 | 0.88 | CYP17A1 (0.45) | MAPK14FFAR4MAP2K4PIK3CDPIK3CA | |
| SCHEMBL8632663 | 0.86 | CYP17A1 (0.48) | MAPK14MAP2K4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL8627628 | 0.85 | FFAR4 (0.44) | RXFP1FFAR4TSHRCYTH2KDM4E | |
| SCHEMBL8631178 | 0.81 | STAT3 (0.47) | MAPK14RXFP1FFAR4TSHRMAP2K4 | |
| SCHEMBL8629484 | 0.81 | MAP2K4 (0.45) | MAPK14MAP2K4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL8632810 | 0.80 | STAT3 (0.42) | MAPK14FFAR4TSHRCYTH2 | |
| SCHEMBL8629394 | 0.80 | KDM4E (0.40) | MAPK14RXFP1FFAR4KDM4E | |
| SCHEMBL8630028 | 0.78 | ALDH1A1 (0.45) | FFAR4TSHRCYTH2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |